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Understanding Hormone Receptors
07/29/2024

What is a hormone receptor, and how do they work? On the inside of every cell there are a large number of molecules called receptors. These receptors are the eyes and the ears of the cell, waiting for messages which they then act upon.

The messages come in the form of chemicals in the bloodstream; hormones are chemical messengers that fit into special hormone receptors.

Hormone Receptors = Mailboxes

Imagine your body as a giant communication network. Hormones are the messages, zipping around in your bloodstream. But how do they know where to go and what to tell each cell? That's where hormone receptors come in – they're the tiny mailboxes waiting for the specific message meant for their cell. Receptors are like protein antennas (think a mailbox with the flag up!) sticking out of your cells, or in some cases, chilling inside the cell itself. Each receptor is designed to fit only one specific hormone, like a key and lock. There are hundreds of different receptors, each waiting for its own hormonal message.

How does it work?

  1. The Mail Arrives: A hormone cruises through your bloodstream until it bumps into the right receptor on a target cell.
  2. Perfect Fit: If the hormone is the correct shape, it clicks into the receptor like a puzzle piece. This binding triggers a reaction within the cell.
  3. Getting the Message Across: Depending on the hormone and receptor type, the message can be delivered in a couple of ways:
    • Calling the Shots: Some receptors are like switchboards, directly turning on or off genes inside the cell. This can lead to changes in how the cell works, like producing more energy or starting to grow.
    • Second Messengers: Other receptors rely on sending a chemical signal inside the cell, like a relay runner. This secondary message can trigger a whole cascade of events, leading to various cellular responses.

An Important Lock and Key System

This specific matching between hormone and receptor is crucial. It ensures that only the intended cells get the message. Imagine what chaos would ensue if junk mail started showing up in your inbox – that's kind of what would happen if hormones could bind to any receptor!

When they fit together or bind, the receptor can initiate multiple signals which ultimately change the behaviors of the target cells. They do things like activate or deactivate genetic messages, transport metabolites, or control enzymatic activity to manage your metabolism.

NLB110-lockandkey(estriolandestrogenreceptor).png

Estriol Receptors

A good example of this is estriol receptors. These are found in various places across a woman’s body: breasts, ovaries, vagina, bones, brain, liver, colon, skin, and salivary gland...to name just a few.

When the hormone estriol connects with a receptor, different actions occur depending on the location. We’re most interested in the large number of estriol receptors located in the vaginal wall. When estriol binds to these receptors, the cells of the vagina send signals to repair the tissue, plump the skin up, and make moisture. And that is what we want.

We’ve heard heartbreaking stories from women who’ve given up on sex because their vagina’s become too dry and friction during sex would tear their skin and from women who are less concerned with sex, but are driven crazy due to constant vaginal itching and irritation.

We know there is a solution – it’s the estriol in the Silky Peach Cream!